About this Candidate
DAVRON CV: Candidate 1930965
SENIOR BIOCHEMIST | MASS SPECTROMETRY, PROTEIN PURIFICATION & HTS ASSAY DEVELOPMENT
Core Expertise
- Protein purification across E. coli, baculovirus, mammalian systems including refolding from inclusion bodies.
- Mass spectrometry specialist: MALDI, triple quad, single quad, and RapidFire platforms for peptides and small molecules.
- High-throughput assay development and implementation; developed eight assays adopted into HTS workflows.
- Chromatography expertise: affinity, IEX, SEC, HPLC, preparative IEF for peptides and recombinant proteins.
- GLP-compliant method development, SOPs, IQ/OQ/PQ documentation, and technical writing for regulated labs.
Project Background
- Advanced drug-discovery support: mass spec and biochemical assays that advanced candidates into clinical evaluation.
- Established and managed analytical labs, selecting instruments and implementing workflow for throughput and compliance.
- Developed lipid-focused assays and modified matrices to enable small molecule and lipid detection under 1000 Da.
- Supervised and trained summer students and junior staff in assay execution and data analysis.
- Led protein characterization using MS, antibody-based methods, and covalent modification mapping.
Key Skills
- MALDI | Triple Quad (Sciex) | Single Quad | RapidFire
- HPLC | Affinity Chromatography | IEX | SEC | Preparative IEF
- Protein expression & refolding | Epitope-tagged protein purification
- HTS assay design | Enzyme kinetics | ELISA | Western blot
- Mass spec data analysis | Protein sequencing | Amino acid analysis
- GLP | SOP | IQ/OQ/PQ | Technical writing
- Biolumix & Petrifilm | Fluorescent atomic absorption
- Plant extraction & natural product analysis | Lipid biochemistry
Education
- M.S., Biochemistry — Southern Illinois University
- B.S., Biochemistry — Purdue University
Why Interview this Candidate?
Seasoned biochemist with 30+ years of hands-on experience in mass spectrometry, protein purification and HTS assay development. Proven record advancing drug-discovery candidates and implementing GLP-compliant lab systems. Brings immediate expertise in chromatography, MS platforms, lipid biochemistry, and assay troubleshooting to analytical and discovery teams.
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